Publications

Yadong Huang, MD, PhDApolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease. View in: PubMed
Yadong Huang, MD, PhDJi ZS, Miranda RD, Newhouse YM, Weisgraber KH, Huang Y, Mahley RW. Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells. J Biol Chem. 2002 Jun 14; 277(24):21821-8. View in: PubMed
Yadong Huang, MD, PhDAstroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease. View in: PubMed
Yadong Huang, MD, PhDHuang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8838-43. View in: PubMed
Yadong Huang, MD, PhDCarboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. View in: PubMed
Yadong Huang, MD, PhDLanger C, Huang Y, Cullen P, Wiesenhütter B, Mahley RW, Assmann G, von Eckardstein A. Endogenous apolipoprotein E modulates cholesterol efflux and cholesteryl ester hydrolysis mediated by high-density lipoprotein-3 and lipid-free apolipoproteins in mouse peritoneal macrophages. J Mol Med (Berl). 2000; 78(4):217-27. View in: PubMed
Yadong Huang, MD, PhDModulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation. View in: PubMed
Yadong Huang, MD, PhDHuang Y, Ji ZS, Brecht WJ, Rall SC, Taylor JM, Mahley RW. Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis. Arterioscler Thromb Vasc Biol. 1999 Dec; 19(12):2952-9. View in: PubMed
Yadong Huang, MD, PhDEvidence for differential effects of apoE3 and apoE4 on HDL metabolism. View in: PubMed
Yadong Huang, MD, PhDMahley RW, Huang Y, Rall SC. Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia). Questions, quandaries, and paradoxes. J Lipid Res. 1999 Nov; 40(11):1933-49. View in: PubMed