Publications

Steve Finkbeiner, MD, PhDMitra S, Tsvetkov AS, Finkbeiner S. Protein turnover and inclusion body formation. Autophagy. 2009 Oct; 5(7):1037-8. View in: PubMed
Steve Finkbeiner, MD, PhDSerines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. View in: PubMed
Steve Finkbeiner, MD, PhDLegleiter J, Lotz GP, Miller J, Ko J, Ng C, Williams GL, Finkbeiner S, Patterson PH, Muchowski PJ. Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment. J Biol Chem. 2009 Aug 7; 284(32):21647-58. View in: PubMed
Steve Finkbeiner, MD, PhDIKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. View in: PubMed
Steve Finkbeiner, MD, PhDMontie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE. Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. Hum Mol Genet. 2009 Jun 1; 18(11):1937-50. View in: PubMed
Steve Finkbeiner, MD, PhDHigh-content screening of primary neurons: ready for prime time. View in: PubMed
Steve Finkbeiner, MD, PhDPintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. J Neurosci. 2009 Feb 4; 29(5):1525-37. View in: PubMed
Steve Finkbeiner, MD, PhDProtein turnover and inclusion body formation. View in: PubMed
Steve Finkbeiner, MD, PhDMitra S, Tsvetkov AS, Finkbeiner S. Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease. J Biol Chem. 2009 Feb 13; 284(7):4398-403. View in: PubMed
Steve Finkbeiner, MD, PhDFinkbeiner S, Mitra S. The ubiquitin-proteasome pathway in Huntington's disease. ScientificWorldJournal. 2008; 8:421-33. View in: PubMed