Publications

Yadong Huang, MD, PhDAlzheimer disease: multiple causes, multiple effects of apolipoprotein E4, and multiple therapeutic approaches. View in: PubMed
Yadong Huang, MD, PhDMahley RW, Huang Y, Weisgraber KH. Detrimental effects of apolipoprotein E4: potential therapeutic targets in Alzheimer's disease. Curr Alzheimer Res. 2007 Dec; 4(5):537-40. View in: PubMed
Yadong Huang, MD, PhDApolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS. View in: PubMed
Yadong Huang, MD, PhDMahley RW, Huang Y. Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing. J Clin Invest. 2007 Jan; 117(1):94-8. View in: PubMed
Yadong Huang, MD, PhDApolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression. View in: PubMed
Yadong Huang, MD, PhDIntron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS. View in: PubMed
Yadong Huang, MD, PhDHuang Y. Molecular and cellular mechanisms of apolipoprotein E4 neurotoxicity and potential therapeutic strategies. Curr Opin Drug Discov Devel. 2006 Sep; 9(5):627-41. View in: PubMed
Yadong Huang, MD, PhDRoses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, Mahley RW. Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease). Pharmacogenomics J. 2007 Feb; 7(1):10-28. View in: PubMed
Yadong Huang, MD, PhDRosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons. View in: PubMed
Yadong Huang, MD, PhDXu Q, Bernardo A, Walker D, Kanegawa T, Mahley RW, Huang Y. Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus. J Neurosci. 2006 May 10; 26(19):4985-94. View in: PubMed