Publications

Steve Finkbeiner, MD, PhDArc regulates spine morphology and maintains network stability in vivo. View in: PubMed
Steve Finkbeiner, MD, PhDMiller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. J Neurosci. 2010 Aug 4; 30(31):10541-50. View in: PubMed
Steve Finkbeiner, MD, PhDPolyQ disease: too many Qs, too much function? View in: PubMed
Steve Finkbeiner, MD, PhDBridging the Valley of Death of therapeutics for neurodegeneration. View in: PubMed
Steve Finkbeiner, MD, PhDRamdzan YM, Nisbet RM, Miller J, Finkbeiner S, Hill AF, Hatters DM. Conformation sensors that distinguish monomeric proteins from oligomers in live cells. Chem Biol. 2010 Apr 23; 17(4):371-9. View in: PubMed
Steve Finkbeiner, MD, PhDA small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model. View in: PubMed
Steve Finkbeiner, MD, PhDLandles C, Sathasivam K, Weiss A, Woodman B, Moffitt H, Finkbeiner S, Sun B, Gafni J, Ellerby LM, Trottier Y, Richards WG, Osmand A, Paganetti P, Bates GP. Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease. J Biol Chem. 2010 Mar 19; 285(12):8808-23. View in: PubMed
Steve Finkbeiner, MD, PhDTau reduction prevents Abeta-induced defects in axonal transport. View in: PubMed
Steve Finkbeiner, MD, PhDBarmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S. Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J Neurosci. 2010 Jan 13; 30(2):639-49. View in: PubMed
Steve Finkbeiner, MD, PhDQuantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis. View in: PubMed