Publications

Ken Nakamura, MD, PhDHertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. (2013) A neo-substrate that amplifies catalytic activity of Parkinson's disease related kinase PINK1. Cell. 154 (737-747). View in: PubMed
Ken Nakamura, MD, PhDNakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem. 2011 Jun 10; 286(23):20710-26. View in: PubMed
Ken Nakamura, MD, PhDNemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010 Jan 14; 65(1):66-79. View in: PubMed
Ken Nakamura, MD, PhDFortin DL, Nemani VM, Nakamura K, Edwards RH. The behavior of alpha-synuclein in neurons. Mov Disord. 2010; 25 Suppl 1:S21-6. View in: PubMed
Ken Nakamura, MD, PhDNakamura K, Nemani VM, Wallender EK, Kaehlcke K, Ott M, Edwards RH. Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria. J Neurosci. 2008 Nov 19; 28(47):12305-17. View in: PubMed
Ken Nakamura, MD, PhDNakamura K, Edwards RH. Physiology versus pathology in Parkinson's disease. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):11867-8. View in: PubMed
Ken Nakamura, MD, PhDNakamura K, Christine CW, Starr PA, Marks WJ. Effects of unilateral subthalamic and pallidal deep brain stimulation on fine motor functions in Parkinson's disease. Mov Disord. 2007 Apr 15; 22(5):619-26. View in: PubMed
Ken Nakamura, MD, PhDNakamura K, Aminoff MJ. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs Today (Barc). 2007 Feb; 43(2):97-116. View in: PubMed
Ken Nakamura, MD, PhDNakamura K Kang UJ. Textbook of neural repair and rehabilitation (eds Selzer ME, Cohen L, Gage FH, Clarke S and Duncan PW). Trophic factor delivery by gene therapy. 2006; 532-547. View in: Custom
Ken Nakamura, MD, PhDFortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci. 2004 Jul 28; 24(30):6715-23. View in: PubMed