Publications

Steve Finkbeiner, MD, PhDInhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. View in: PubMed
Steve Finkbeiner, MD, PhDWray S, Self M. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. PLoS One. 2012; 7(8):e43099. View in: PubMed
Steve Finkbeiner, MD, PhDProgranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. View in: PubMed
Steve Finkbeiner, MD, PhDBilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, Wilmut I, Finkbeiner S, Maniatis T, Shaw CE, Chandran S. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15):5803-8. View in: PubMed
Steve Finkbeiner, MD, PhDMiller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol. 2012; 8(3):318. View in: PubMed
Steve Finkbeiner, MD, PhDCreation of an open-access, mutation-defined fibroblast resource for neurological disease research. View in: PubMed
Steve Finkbeiner, MD, PhDNucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Identification of Novel Potentially Toxic Oligomers Formed in Vitro from Mammalian-derived Expanded huntingtin Exon-1 Protein. J Biol Chem. 2012 May 4; 287(19):16017-28. View in: PubMed
Steve Finkbeiner, MD, PhDMiller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol. 2012; 8(3):318. View in: PubMed
Steve Finkbeiner, MD, PhDMiller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol. 2012; 8(3):318. View in: PubMed
Steve Finkbeiner, MD, PhDMethylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models. View in: PubMed