Publications

Li Gan, PhDCho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM, Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. J Biol Chem. 2011 Sep 16; 286(37):32713-22. View in: PubMed
Li Gan, PhDCX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. View in: PubMed
Yadong Huang, MD, PhDChen HK, Liu Z, Meyer-Franke A, Brodbeck J, Miranda RD, McGuire JG, Pleiss MA, Ji ZS, Balestra ME, Walker DW, Xu Q, Jeong DE, Budamagunta MS, Voss JC, Freedman SB, Weisgraber KH, Huang Y, Mahley RW. Small molecule structure correctors abolish detrimental effects of apolipoprotein e4 in cultured neurons. J Biol Chem. 2012 Feb 17; 287(8):5253-66. View in: PubMed
Yadong Huang, MD, PhDDirect reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. View in: PubMed
Anatol Kreitzer, PhDHarwell CC, Parker PR, Gee SM, Okada A, McConnell SK, Kreitzer AC, Kriegstein AR. Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation. Neuron. 2012 Mar 22; 73(6):1116-26. View in: PubMed
Robert W. Mahley, MD, PhDBrodbeck J, McGuire J, Liu Z, Meyer-Franke A, Balestra ME, Jeong DE, Pleiss M, McComas C, Hess F, Witter D, Peterson S, Childers M, Goulet M, Liverton N, Hargreaves R, Freedman S, Weisgraber KH, Mahley RW, Huang Y. Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors. J Biol Chem. 2011 May 13; 286(19):17217-26. View in: PubMed
Robert Mahley, MD, PhDNovel Loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. View in: PubMed
Lennart Mucke, MDMinami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots. J Neuroinflammation. 2012; 9:22. View in: PubMed
Lennart Mucke, MDInhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. View in: PubMed
Ken Nakamura, MD, PhDNemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll RA, Edwards RH. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010 Jan 14; 65(1):66-79. View in: PubMed