Gladstone in the News

The Gladstone Institutes is gratified to receive media attention from around the globe. Check out the highlights of recent press coverage of Gladstone scientists and research. For other news, please be sure to follow us on Facebook and Twitter.

HIV infection causes immune cells to self-destruct, study says
December 19, 2013

Scientists say they have discovered a key process by which the AIDS virus kills key immune cells: It triggers a preprogrammed self-destruct sequence within the cell that is intended to alert fellow immune cells of a crisis.

Gladstone HIV researchers target Vertex drug for clinical trial
December 19, 2013

An anti-inflammatory drug shelved by Vertex Pharmaceuticals Inc. after a mid-stage study in epilepsy patients could be the next big HIV treatment.

Scientists Discover Mechanism of Immune System Cell Death in AIDS
December 19, 2013

Scientists have discovered that the AIDS virus destroys the immune system by infecting a relatively few number of cells that create a fiery pathway that consumes nearby cells. Finding could lead to treatments to dampen disease activity.

Twin U.S. studies unlock mystery of how HIV causes AIDS
December 19, 2013

U.S. scientists have discovered the basic mechanisms that allow HIV to wipe out the body's immune system and cause AIDS, which could lead to new approaches to treatment and research for a cure for the disease that affects 35 million people around the world.

Drug blocks HIV in lab study, human tests planned
December 19, 2013

Can an experimental drug developed to treat epilepsy block the AIDS virus? A preliminary lab study suggests it's possible, and researchers are eager to try it in people.

HIV's Killer Tactics Revealed, New Therapy Approach Found
December 19, 2013

The reason people who are infected with HIV die is because their white blood cells die, leaving them unable to fight infections. Now, researchers show for the first time that this cell death is caused by cellular self-destruction, and is linked with inflammation.

HIV Mechanism: 'Suicide, not Murder'
December 19, 2013

In uncontrolled HIV infection, an over-the-top immune response causes much of the damage that leads to AIDS, researchers are reporting.

Cell-suicide blocker holds promise as HIV therapy
December 19, 2013

HIV infection causes a mass suicide of immune cells — a process that can be halted by an experimental drug that blocks cellular self-destruction, studies in cell cultures suggest. Researchers are now proposing a clinical trial of the drug in people with HIV.

How HIV Destroys Immune Cells
December 19, 2013

HIV leads to AIDS primarily because the virus destroys essential immune cells called CD4 T cells, but precisely how these cells are killed has not been clear. Two papers published simultaneously today (19 December) in Nature and Science reveal the molecular mechanisms that cause the death of most CD4 T cells in lymphoid tissues, the main reservoir for such cells, during infection.

Does Truvada, The HIV-Prevention Pill, Increase Sexually Risky Behavior?
December 18, 2013

In July 2012, the Food and Drug Administration (FDA) approved Truvada, the first and only drug intended to prevent HIV infection. Now, a new study provides more proof that regular use of Truvada (emtricitabine and tenofovir disoproxil fumarate) can reduce an individual’s risk of contracting HIV by more than 90 percent. Importantly, the researchers also found that use of the pill does not equate to an increase in risky sexual behavior.