Gladstone in the News
The Gladstone Institutes is gratified to receive media attention from around the globe. Check out the highlights of recent press coverage of Gladstone scientists and research. For other news, please be sure to follow us on Facebook and Twitter.
A new study by U.S. scientists revealed a way to alleviate the learning and memory deficits caused by a gene linked to Alzheimer's disease. By transplanting new cells into the brain, they saw improved brain activity, restoring cognition to normal levels in elderly mice.
With more than 5 million Americans living with Alzheimer's disease, the race is on to develop new treatments for the condition. Now, researchers from the Gladstone Institutes in San Francisco, CA, and the University of California-San Francisco reveal they have successfully reversed learning and memory deficits in mouse models of Alzheimer's through transplantation of healthy brain cells.
Compounds that boost the 'noise' in genetic activity of HIV can reactivate the latent virus. Such drugs could make it easier to stamp out quiescent HIV infections.
Bumping up the random "noise" associated with HIV gene expression can help reactivate the virus in cells where it has been latent, making it easier to find and kill, according to research from San Francisco Gladstone Institutes.
It’s the latest in gene therapy, and it’s lowered cholesterol and heart attacks in mice. People are next.
A team of scientists at the Gladstone Institutes has identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection. They discovered that increasing the random activity, or noise, associated with HIV gene expression - without increasing the average level of gene expression - can reactivate latent HIV. Their findings were published in the journal Science.
From human induced pluripotent stem cells, researchers grow 3-D retinal tissue that can sense light.
Findings published yesterday in the journal Science by a team of scientists at the Gladstone Institutes identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection. The scientists discovered that increasing the random activity, or noise, associated with HIV gene expression—without increasing the average level of gene expression—can reactivate latent HIV.
For decades, most researchers ignored the leading genetic risk factor for Alzheimer's disease. That is set to change, thanks in large part to pioneers at Gladstone.
Three scientists, including Gladstone's Melanie Ott, MD, PhD, have been chosen to receive the 2014 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. The three scientists will each receive $500,000 per year for five years to support their research.