Gladstone in the News
The Gladstone Institutes is gratified to receive media attention from around the globe. Check out the highlights of recent press coverage of Gladstone scientists and research. For other news, please be sure to follow us on Facebook and Twitter.
Beating heart muscle can be converted quickly and efficiently from other cardiac cells by directly injecting three genes into areas damaged by a heart attack, according to researchers at the J. David Gladstone Institutes.
A study published Wednesday in the journal Nature revealed that scientists have managed to convert damaged tissue into functioning heart muscle by inducing mild heart attacks on lab mice then coaxing their hearts into rebuilding themselves.
In an act of transformation worthy of any magician, scientists have converted scar tissue in the hearts of living mice into beating heart cells. If the same trick works in humans, it could lead us to a long-sought prize of medicine – a way to mend a broken heart.
When the history of the AIDS epidemic is written, I hope there will be a chapter on Dr. Robert Grant, a professor of medicine at the University of California, San Francisco, and at the Gladstone Institute of Virology and Immunology.
CIRM grantees at the Gladstone Institutes in San Francisco have carried out a remarkable feat: They directly converted scar-forming cells in the mouse heart into beating cells.
Researchers from the Gladstone Institutes in the US showed for the first time that injecting a combination of genes into the damaged heart tissue of a living animal could make it beat again.
Researchers from the Gladstone Institutes successfully converted scar tissue in the mice into beating heart muscle. Their findings, they said, might eventually lead to a similar treatment for people who've had heart attacks.
Deepak Srivastava, director of the Gladstone Institute of Cardiovascular Disease, led a team in reprogramming cardiac fibroblasts into cardiomyocytes—the muscle cells of the heart that are permanently lost after a heart attack.
One of the ultimate ways of understanding what impact any particular gene has in human health or disease is to disrupt it.
New research reveals new developments to reprogram scar tissue, that is a result from myocardial infarction, into heart muscle cells.